50 bool tests would take no time at all. You'd have to worry more about different overheads from the number of gameobjects/fsms.
And 50 isn't much at all. I have 400 FSMs doing all sorts of stuff every frame, without issue.
EDIT: This gives me an idea to add stop stopwatch actions if they don't already exist. Would be nice to profile stuff in PlayMaker without UnityPro.