I don't think there are any specific guides for that, those games are very data driven.
It's really not terribly difficult to do, most of the game is handled on the back end. Plague Inc you barely see more than the world map and the upgrade menu that is quite simplistic. Everything that really composes the game is data driven on the backend with minimal feedback to the world map for you to see during the game really.
Its similar to the way other games manage things, the Plague is basically a stack of stats that you can upgrade by spending some points, and the game plays off that data, like probability of an infected country infecting across a land border, or sending infection via plane/boat. Its just a roll of the dice every time the event comes around to be calculated as yes/no all based on the country's stats against the plague's stats and upgrade numbers.
Playmaker does fine with stuff like that, have you checked out the beginner tutorials and stuff yet? You should be able to get going with something simple after learning how to read/share data between fsm's.